Q.30: Write a note on Heart beat?
Ans:
Heart BEATS:
When chambers of the heart contract in a systematic and regular manner, it is called a heartbeat. A normal heart shows 72 beats per minute. Heartbeats are also known as heart sounds, which can be listened to easily. Heartbeat begins before birth and continues until death.
During a heartbeat, when the ventricles contract (systole), blood is pushed against the closed atrioventricular (AV) valves, producing the first sound ("LUB"). Following systole, the ventricles relax (diastole), and high pressure in the aorta forces some blood back toward the ventricles, closing the aortic valves, producing the second sound ("DUP"). Each heartbeat cycle includes one systole and one diastole, taking about 0.8 seconds. When there is a defect in one or more valves, it may cause a "heart murmur," detectable as a hissing sound.
Q.31: What is Sino-atrial node (S-A Node)?
Ans:
SINO-ATRIAL NODE (S-A NODE):
The sino-atrial node, located at the top of the right atrium near the superior vena cava, generates electrical impulses and initiates heart contractions, earning it the nickname "pacemaker." It comprises cardiac muscle fibers with few nerve endings from the autonomic nervous system.
Q.32: What is Atrio-ventricular node (A-V Node)?
Ans:
ATRIO-VENTRICULAR NODE (A-V NODE):
Located below the S-A node in the right atrium, the A-V node transfers excitation to all parts of the ventricles through muscle fiber bundles. It includes fibers of the bundle of His and Purkinje fibers, which propagate impulses throughout the ventricular walls. A delay of 0.15 seconds occurs between the S-A and A-V nodes to complete atrial systole before ventricular systole.
Q.33: Describe different blood diseases of man?
Ans:
DISEASES OF BLOOD:
Leukaemia:
A blood cancer caused by the uncontrolled production of white blood cells (WBCs), leading to their increase. Bone marrow cells spread through the body, disrupting normal WBC formation. Symptoms include frequent bleeding, and treatment options include bone marrow transplantation, although this is expensive.
Thalassemia:
A genetic disorder causing reduced hemoglobin production. In severe cases, patients need regular blood replacement. Children with thalassemia may have an enlarged spleen and kidneys.
Q.34: What is artificial pacemaker?
Ans:
ARTIFICIAL PACEMAKER:
When the natural pacemaker (S-A node) fails, an artificial pacemaker, which supplies electrical impulses to maintain a regular heartbeat, is implanted under the chest skin, powered by battery or electrical wires.
Q.35: What are blue babies?
Ans:
BLUE BABIES:
A condition in newborns characterized by blue skin (cyanosis) due to oxygenated and deoxygenated blood mixing, often caused by defects in the heart's septum.
Q.36: Describe different kinds of blood vessels?
Ans:
BLOOD VESSELS:
The vessels through which blood flows are called blood vessels. These vessels carry blood from the heart to body organs and bring back the blood from body parts to the heart.
The blood vessels are of two types:
ARTERIES:
Arteries are the blood vessels which carry the blood from the heart to different parts of the body. Their walls are composed of three layers.
- Tunica externa: outer layer
- Tunica media: middle layer
- Tunica interna: inner layer
Outer Layer:
It is composed of connective tissues which are hard and fibrous, called collagen fibers. They can resist the internal blood pressure.
Middle Layer:
It consists of smooth muscles which are elastic. By their contraction and relaxation, their cavity (lumen) can be decreased or increased. They also control the amount of blood. The cavity of arteries is smaller than veins.
Inner Layer:
It is made up of an endothelial layer. The smallest arteries are called arterioles which control the flow of blood into the capillaries. The arterioles contain valves (sphincters) at their capillary ends, which control the blood flow into capillaries. The arteries carry oxygenated blood from the heart to different parts of the body, but in pulmonary arteries, deoxygenated blood is present, which is carried to the lungs.
VEINS:
The blood vessels which carry the blood from various parts of the body back to the heart are called veins. They are thin-walled vessels. Their walls are composed of three layers.
Outer Layer:
It is made up of hard and fibrous connective tissues, known as collagen fibers.
Middle Layer:
It has smooth elastic muscles.
Inner Layer:
It consists of endothelial layer.
The inner cavity (lumen) of veins is much larger than arteries. The veins have valves which prevent the backward flow of blood. Due to the larger diameter of veins, there is less resistance in the flow of blood, and it can flow in large volume. The smallest veins are called venules which obtain blood from capillaries. The largest vein is termed as caval vein which enters the heart. The veins contain deoxygenated blood except pulmonary veins, which bring blood from lungs to the heart.
Capillaries:
In the transport system, the function of blood circulation is to supply the important materials from one part to another. In this way, a close contact is necessary between circulation and tissues. This contact is in the form of blood capillaries. These are very fine blood vessels which are thin-walled and narrower than arteries and veins. Their diameter is about 7-10.
The wall of capillaries consists of a single layer, called endothelium, through which the diffusion of substances occurs easily. The capillaries are connected to the cells and tissues, so the exchange of important materials between tissue fluid and blood of capillaries takes place by diffusion or active transport. From the blood, O2 is diffused out into body tissues and CO2 of tissues is diffused into the blood. Blood capillaries also help to filter the harmful nitrogenous substances into the excretory organs for their excretion.
Q.37: Write a note on blood pressure?
Ans: BLOOD PRESSURE:
The hydrostatic force exerted by the blood against the walls of blood vessels is called blood pressure. This pressure is produced by the ventricle systole i.e. contraction of ventricles. It helps in the flow of blood from the heart to all parts of the body. When blood flows in the arteries, their walls are stretched due to elasticity, it is called pulse. This pulsation can be felt easily.
Blood pressure is measured in millimeters of Hg (Mercury). Mercury manometer is widely used throughout the world, called sphygmomanometer. The blood pressure is determined by cardiac output and by the diameter of arterioles. When constriction takes place in the walls of arterioles, it is called vasoconstriction. It rises the blood pressure and when walls of arterioles are dilated, it is called vasodilatation, it falls the blood pressure. The smooth muscles of arterioles help in constriction and relation of arterioles and these muscles are controlled by nerve impulses and hormones.
In a normal healthy person the blood pressure during systole is about 120mm high, visible in the glass tube of monometer and during diastole of ventricles is about 80mm high. It is expressed as Blood Pressure (B.P) of 120/80. The difference between systolic and diastolic pressure is called pulse pressure.
Blood Flow:
The flow of blood is very fast in larger arteries. It is highest in aorta, and then gradually reduces in arteries and much slower in capillaries. The total diameter of capillaries is greater than arteries, so the blood flows slowly in capillaries. It helps in the exchange of materials between blood and interstitial tissues.
Drainage System:
The lymphatic vessels take part in the returning of water and plasma proteins back to the bloodstream, which have leaked away from blood. Otherwise, death may occur in 24 hours.
Defence Of The Body:
The lymphatic system helps to maintain body resistance. The microorganisms, foreign bodies, and broken cells are removed by macrophages found in the lymphatic nodes.
Absorption And Delivery Of Fats:
The lacteals of villi absorb digested fats, which are changed into droplets. After that, these fats are returned back to the blood.
Bathing Of Tissues:
The lymphatic vessels bathe the tissues and keep them moist.
(Image of the Lymphatic System of Man)
Q.38: Describe Lymphatic System in the body of man?
Ans: LYMPHATIC SYSTEM:
Lymph is a tissue fluid, passes out from the walls of capillaries into the space surrounding the cells. It is actually obtained from the blood-plasma. It is colorless and without proteins. It is involved in osmotic changes between cell-protoplasm and blood.
The lymph passes through vessels, called lymphatic vessels. They form a separate network and constitute the lymphatic system. These vessels carry the fluid to the heart and blood. These vessels also contain valves due to which the backward flow is prevented. In addition to lymphatic vessels and lymph, this system also consists of lymph nodes, spleen, thymus, tonsils and some patches of tissues in appendix and small intestine.
Lymph Capillaries:
The lymph vessels produce lymph capillaries, which form a network in every organ except the nervous system. The lymph capillaries unite together to form larger lymphatic vessels; these are connected with subclavia vein.
Lacteals:
Within the villi of intestine, the lymph vessels are called Lacteals. The lymph circulates through the lymph vessels by the contraction of skeletal muscles in one direction i.e. to the heart. These vessels form collecting ducts, which are connected with veins in the lower neck.
Lymphatic Nodes:
At certain points, the lymph vessels contain special masses of connective tissues, called lymph nodes. In these nodes, lymphocytes are present. Lymphocytes are the cells of the immune system. Through lymph nodes, lymph is filtered. The lymph nodes are of different size, from microscopic size to one inch. Many lymphatic vessels carry the lymph into the lymphatic node, but from this node, a single large vessel comes out. When lymph is filtered through the lymph nodes, the lymphocytes and macrophages present here neutralize it and kill the microorganisms.
Functions Of Lymphatic System:
The lymphatic system performs the following functions:
Q.39: Write a note on Edema?
Ans: EDEMA:
Edema is an "Abnormal condition" caused by lymphatic system when it is not functioning normally. When tissue fluid is not returning into the blood by lymphatic system and it is accumulated in the body tissues and it causes swelling, it is called edema. The excess fluid may be in the cells or outside the cells. Edema results in high blood pressure, kidney failure and heart failure etc.
Causes Of Edema:
- Protein deficiency causes edema. When proteins are not used in food, the body consumes its own blood proteins, so blood cannot absorb tissue fluid, it is accumulated in the body tissues. It causes edema.
- Lymphatic system becomes fail to return fluid due to any obstruction, it results edema.
- When renal system retains salts and water, it causes edema.
- Filariasis is also a cause of edema. It is a disease due to nematodes.
- Due to burns or allergic reactions permeability of capillaries is increased, It causes edema.
Q.40: Name the various cardiovascular diseases?
Ans: CARDIOVASCULAR DISORDERS (CVD):
Diseases of heart, blood vessels and blood circulation are known as cardiovascular disorders (CVD). Some of these disorders are as follows:
- Atherosclerosis
- Hypertension
- Thrombus formation
- Coronary thrombosis
- Myocardial infarction (Heart attack)
- Stroke
- Haemorrhage
Q.41: Write a note on Atherosclerosis?
Ans: ATHEROSCLEROSIS:
Atherosclerosis is the disorder of blood vessels, in which arteries become harden. The inner walls of arteries become narrow, lose their elasticity, due to the formation of raised patches of fats in their inner lining, called athermanous plaques. In such condition flow of blood is disturbed. These raised patches consist of low density lipoprotein (LDL) i.e. cholesterol and proteins, fibrous tissues, decaying muscle cells, clusters of blood platelets or calcium.
Causes:
The causes of atherosclerosis are:
Q.42: What is Hypertension?
Ans: HYPERTENSION:
When the blood pressure is higher than the normal blood pressure, it is called hypertension and the person is called hypertensive. When under resting condition the mean arterial pressure is greater than 110 mmHg, it is considered as high blood pressure and hypertension. It takes place when diastolic blood pressure is greater than 90mmHg and systolic blood pressure is greater than 135-140 mmHg.
Causes:
The causes of high blood pressure hypertension are:
- Use of higher amount of salts in food
- Hereditary factor
- Smoking
- Obesity (Fatness)
- Disorders of kidneys or adrenal glands
Effects:
- Continuous high blood pressure damages the lining of blood vessels, so heart muscles become weak, and its pumping function is affected.
- It causes stroke or heart attack, even no symptom earlier, so it is called silent killer.
- It promotes atherosclerosis.
- Heart may be enlarged.
Q.43: What Is Thrombus formation?
Ans: THROMBUS FORMATION:
The clotting of blood in the blood vessels is called thrombus formation. The main cause of thrombus is atherosclerotic plaques i.e. patches of fats in the blood vessels. These patches damage the inner layer endothelium of blood vessels, then in the damaged regions platelets are deposited, it results blood clotting. By the continuous process the inner cavity lumen of arteries becomes narrow or blocked. it reduces or stops the blood supply.
Q.44: What is Coronary Thrombosis?
Ans: CORONARY THROMBOSIS:
When thrombus i.e. blood clot occurs in coronary arteries (arteries which supply blood to heart muscles) and these arteries are narrowed or blocked, it is called coronary thrombosis. Due to thrombosis O₂ is not supplied to any part of heart, so it becomes inactive or dead. It causes coronary heart disease. By thrombosis heart attack may occur.
Q.45: Write a note on myocardial infarction (Heart attack)?
Ans: MYOCARDIAL INFARCTION (HEART ATTACK):
When the blood vessels of heart are blocked either by thrombus (clotting of blood) or embolus (clotted blood comes into serum), it causes death of the part of heart and continuous chest pain, it is called myocardial infarction, commonly it is known as heart attack.
When the coronary arteries of heart are blocked and they do not supply O₂ to particular organs, that heart muscle does not work properly and gradually become dead. Such muscles of heart are called infracted and the mechanism is known as myocardial infarction. When a small part of heart is damaged, the person may recover from heart attack, but when large part is damaged, it may cause death of person.
Precautions:
- Persons should not use fatty food, rich with cholesterol.
- Body should not be over-weight.
- Blood pressure should be maintained normal by exercise.
- Smoking should be avoided.
Q.46: Write a note on stroke?
Ans: STROKE:
When any blood vessel in the brain is blocked by blood clotting (thrombus) or embolus (transfer of clotted blood in serum) and there is no proper supply of blood to the brain or sometime there is leakage of blood from blood vessels, it causes a stroke. As a result of stroke the parts of the body are paralyzed which are controlled by damaged part. The sensation, movement or function of these parts is badly affected. When any one cerebral hemisphere is damaged, it causes weakness or paralysis of one side of the body, it is called hemiplegia.
Q.47: What is Hemorrhage?
Ans: HEMORRHAGE:
When there is leakage or discharge of blood from blood vessels, it is called hemorrhage. When any blood vessel in the brain is ruptured, it causes brain hemorrhage. It is very serious and dangerous. The main cause of brain hemorrhage is hypertension. The massive accumulation of blood within the tissue is called hematoma.
Q.48: What is immune system? What are the types of immune system?
Ans: THE IMMUNE SYSTEM:
The ability of a living organism to resist the infection by parasitic microorganisms, their toxins, foreign cells or abnormal cells of the body is called immunity, and the system which shows response to the infection is known as immune system. Immunity is an essential requirement for survival, since the body of man and animals is attacked by viruses, bacteria, fungi, and parasitic animals.
Types Of Immune System:
There are two types of immune system.
- Innate immune system
- Adaptive immune system
Q.49: Describe the innate immune system?
Ans: INNATE IMMUNE SYSTEM (NON-SPECIFIC IMMUNE SYSTEM)
It is the natural immune system and non-specific, i.e., this immunity prevents the infection of all microorganisms. This system is responsible to control the activity of microorganisms. In innate immune system there are two systems of defense.
- Physical body organs (First line of defence)
- Internal body system (Second line of defence)
Physical Body Organs: (First Line Of Defence)
Skin and mucous membrane are very important organs, which act as the first line of defence i.e., prevent the attack of microorganisms. Skin does not allow the entry of infectious agents. Mucous membrane is present along the lining of digestive, respiratory, and urogenital tracts. Through the mucous membrane, microorganisms can enter the body, but mucus and certain secretions destroy these microorganisms.
Internal Body System: (Second Line Of Defence)
When due to certain reasons microorganisms enter the body, there is another line of defence for the protection of the body from microorganisms. These are:
- Phagocytes
- Antimicrobial proteins
- Inflammatory response
Phagocytes:
These are a type of W.B.C. These cells destroy microorganisms and other particles.
Antimicrobial Proteins:
In the body, certain proteins are produced which destroy infectious microorganisms; these are called antimicrobial proteins.
Inflammatory Response:
It is the condition of fire in any certain part of the body due to any injury or infection of microorganisms. In such a condition, the infected part becomes swollen, reddish, and feels heat and pain.
By infection and inflammation, fever is caused in warm-blooded animals. It is due to the release of a substance by certain W.B.C.s, called pyrogen. It increases the body temperature. Moderate fever is useful to the body because it prevents the growth of microorganisms.
Q.50: Describe the adaptive immune system?
Ans: ADAPTIVE IMMUNE SYSTEM: (SPECIFIC IMMUNE SYSTEM)
It is the specific immune response against specific microorganisms, which is developed in the body specifically against many organisms, tumor cells, transplanted tissues, and toxins. It is considered as third line defence and works with the second line defence system. It is also called specific immune response system. In adaptive immune system, special types of lymphocytes play an important role, called B-cells and T-cells. These cells are produced in bone marrow or thymus.
In adaptive immune system, two types of immunity are developed.
- Humoral immunity: (HI)
Immunity develops due to B-cells against bacteria. - Cell mediated Immunity: (CMI)
Q.51: What are the hormones of immune system?
Ans: HORMONES OF IMMUNE SYSTEM (CYTOKINES OR LYMPHOKINES):
The hormones of the immune system are called cytokines or lymphokines. These are protein molecules. These hormones regulate the immune responses. There are many hormones, such as interleukins (IL), interferons. Interferon's are used in response to viral infection and other stimuli. They control the growth of viruses and increase the activity of natural killer cells (NK cells).
Q.52: Describe primary and secondary immune responses?
Ans: PRIMARY & SECONDARY IMMUNE RESPONSES:
When there is the first entry of an antigen to form effect or cells, there is a response in the immunity system, it is called primary immune response. From the time of infection to the formation of maximum effect or cells 5 to 10 days are required. When there is a second infection by the same pathogen, the response takes place more quickly and rapidly by the immune system, it is called secondary immune response. The time for this response is 3 to 5 days. This quicker response is due to immunological memory of the immune system. During the primary immune response, some memory cells are formed. These cells play a role in the quicker secondary response, and also help in lifelong protection against some dangerous diseases like chicken pox.
Q.53: Describe active and passive immunity?
Ans: ACTIVE & PASSIVE IMMUNITY:
According to the function, there are two types of immunity:
- Active immunity
- Passive immunity
Active Immunity:
The immunity develops by the response of the own immune system of the body, it is called active immunity. It is of two types:
- Natural Active Immunity:
When the immune system is developed in the body by its own response in a natural way, it is called natural active immunity. - Artificial Active Immunity:
Active immunity can be developed artificially by vaccination; it is called artificial active immunity. By vaccination, long-life protection is provided, for example, chicken pox.
Passive Immunity:
When antibodies are introduced into the body from another person or an animal, it is called passive immunity. This immunity may be natural or artificial.
Natural Passive Immunity:
In natural passive immunity, the antibodies are transferred from the body of a person to another person of the same species. For example, antibodies from the mother are transferred into the body of a newborn baby through the placenta.
Artificial Passive Immunity:
In artificial passive immunity, antibodies are obtained from the body of animals or human beings who are already immune to that disease, and these are transferred into another person. For example, antibodies for rabies are obtained from already vaccinated persons and then introduced into the body of an affected person. It is a rapid process of immunity, but it is also short-lived.
Q.54: What is immunization?
Ans: IMMUNIZATION:
Immunization is the resistance against diseases, carried out by vaccination. By effective vaccination, many dangerous diseases have been controlled properly throughout the world, such as diphtheria, measles, polio, smallpox, and hepatitis. Immunization was first introduced by the scientist Edward Jenner.